The film stars Gabriel LaBelle (The Predator, American Gigolo series) as 16-year-old aspiring filmmaker Sammy Fabelman; four-time Academy Award® nominee Michelle Williams (Manchester by the Sea, My Week with Marilyn) as his artistic mother, Mitzi; Paul Dano (The Batman, There Will Be Blood) as his successful, scientific father, Burt; Seth Rogen (Steve Jobs, An American Pickle) as Bennie Loewy, Burt’s best friend and honorary “uncle” to the Fabelman children, and Academy Award® nominee Judd Hirsch (Uncut Gems, Ordinary People) as Mitzi’s Uncle Boris.